Public Health England

Public Health England

Name of leader and affiliation
Dr Joanna Bacon (in-vitro models in WP1 and 3), Dr Sally Sharpe (in-vivo models in WP2 and 3), Dr Ann Rawkins nee Williams, WP2 leader.

The Microbiology Services Division of Public Health England at Porton Down conducts research into a range of microbial pathogens (pathogenicity studies, vaccine development, GMP production of materials for clinical trials, etc), and has extensive ACDP containment level 3 facilities (21 labs & 17 animal rooms).There is a large TB Programme which aims to contribute to the global effort to control tuberculosis through the development and evaluation of therapeutic interventions. Expertise and specialist facilities for studies of the pathogenesis of Mycobacterium tuberculosis are combined with a rare capability to conduct aerosol-infection in vivo studies. State of the art aerosol-challenge and husbandry facilities combined with a strong track record in aerobiology, microbiology, immunology and animal model development make the team at HPA Porton the leading capability for in-vivo models of TB in Europe if not globally.

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The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreement n° 115337, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution.

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